import gzip
import os

outfilename = 'example.txt.gz'
output = gzip.open(outfilename, 'wb')
try:
    output.write('Contents of the example file go here.\n')
finally:
    output.close()

print outfilename, 'contains', os.stat(outfilename).st_size, 'bytes of compressed data'
os.system('file -b --mime %s' % outfilename)

$ python gzip_write.py

application/x-gzip; charset=binary
example.txt.gz contains 68 bytes of compressed data